| Group | Club/Team Name | Team ID | Head Coach |
| A1 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2008 Boys |
03040-001CB6U-0008 | Richard Reynolds |
| A2 | Southside Soccer Club GSC Levante UD 2008 Boys |
03012-001PB6U-0006 | Mobolaji Adeisa |
| A3 | James Island Youth SC JIYSC 2008 Boys Black |
03001-0011B6U-0046 | Comert Pehlivan |
| A4 | Kickoff Soccer Academy - 01 KOSA 2008 Boys CBDF |
03033-001C1B6U-0069 | Efrain Alanis |
| A5 | Kickoff Soccer Academy - 01 KOSA 2008 Boys Yellow |
03033-001C1B6U-0005 | Hector Alejandro Garcia |
| A6 | South Carolina Surf Soccer Club SC Surf 08 Blue |
03008-001CLB6U-5628 | Andrew Kephart |
| B1 | Augusta Arsenal Soccer club - 01 AASC 08 Boys Gold |
02224-001CB6U-0100 | Chris Newman |
| B2 | Bulls Soccer Club KEEP Bulls 08-09 Boys NA U16 |
02012-0031B6U-2639 | Jason Spinks |
| B3 | Congaree Rapid FC - 01 CRFC Sky 08 Boys |
02035-0011B6U-0012 | Kevin Heise |
| B4 | Hartsville United Soccer League - 01 HUSL Warriors FC - Columbia |
02229-001C1B6U-0001 | James Whitaker |
| B5 | Lexington Soccer Academy Lexington SA 08 B Elite |
02004-001IB6U-5200 | John Rosier |
| B6 | South Carolina United FC - Competitive SCUFC 08 Boys Challenge Red |
02208-2081B6U-0639 | Chase Battafarano |
| B7 | Technical Soccer Club - 01 TSC U16 Boys |
02226-0011B6U-8563 | Seward Suarez |
| C1 | CESA Competitive CESA Pachuca 08B Select |
01001-0011B6U-1434 | Carlos Buitrago Millan |
| C2 | CESA Competitive CESA 08B Select Black |
01001-0011B6U-0029 | Jonathan Scrivner |
| C3 | Easley Soccer Club ESC 08 Boys Select |
01019-0011B6U-9479 | Alessio Malaggi |
| C4 | Greenville Metro FC GMFC - U16 BOYS |
01038-001CB6U-0039 | Daniel Albert Diaz |
| C5 | Ninety Six PUMAS - 01 Ninety Six PUMAS - 01 - B16U |
01047-001C1B6U-0031 | Archie Ferqueron |
| C6 | United FC United FC 08B Select |
01032-0011B6U-0011 | Dawson Martin |